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Is Aging Reversal Possible With Gerovital? (Part III)
Chapter 10 from "Nutrients to Age Without Senility" by Abram Hoffer, M.D., Ph.D. and Morton Walker, D.P.M

ENZYMATIC AND BIOCATALYTIC ACTIONS
Procaine's effect on the body's nervous system has a direct effect on the enzymes in the body. Many noted scientists feel that the degeneration of enzymes is part of the aging process. Dr. Albert White of the Albert Einstein College of Medicine wrote a paper on the aging process in the Journal of the American Association for the Advancement of Science. He stated this opinion on enzymes:

The whole gamut of enzyme chemistry seems to be involved. A gradual shift of rate and directions seems to occur in the huge complex of enzyme regulation of the internal steady state in the cells, tissues, and the organism as a whole. This alteration in enzyme activity may be the real beginning of senescence.

Another authority on enzymes and the nervous system, Dr. Ivan P. Pavlov, felt that aging was caused by damage to the nervous system, particularly the cerebral cortex. Dr. Pavlov has shown that should it be possible to influence the nervous system, a change of metabolism and enzymatic processes may be achieved.

Dr. Aslan's GH3 therapy acting on the nervous system contributes to healthful action of the cells to produce proper enzyme action, which in turn is regulated by the nervous system. No claim has ever been made by Prof. Aslan in any of her published papers that she has made a new drug discovery. However, by using GH3 over an extended period of time and in certain prescribed doses, perhaps she has found new uses for the drug's ability to retard the aging process.

The chemical formula for procaine HCL is C13H2002N2HCL. Its generic or chemical name is para-aminobenzoic diethylaminoethanol hydrochloride or procaine HCL. It is composed of small colorless crystals soluble in water.

Biochemists have long known that the human liver produces a specific enzyme called procainesterase, which breaks down the para-aminobenzoic diethylaminoethanol releasing para-aminobenzoic acid to the body. This may well be a clue to the possible important role played by GH3 in basic biochemical processes.

Procaine HCL is one of the few substances that completely alters its chemical composition when administered. It will be recalled that procaine is rapidly hydrolyzed in the body with the formation of p-aminobenzoic acid and diethylaminoethanol.

P-aminobenzoic acid (PABA) has strong biocatalytic action. It was first regarded as a vitamin-like substance because of its biocatalytic action on such living organisms as yeast. It will, as well as procaine, inhibit sulfanilamide activity. It is not necessarily contraindicated if cognizance is taken of this effect. PABA has been used successfully in treating rheumatism, arthritis, and senile changes of the skin and hair. Procaine HCL's aggregate of actions is that it can exert simultaneously: analgesic, sympatholytic and vasodilating; secondarily, parasympathetic and anti contracting.

THE PRESENT TREATMENT METHODS
It is entirely feasible that men of science may successfully construct the component part of Gerovital H3 in a tablet. Biochemists call p-aminobenzoic acid vitamin H-1. The far reaching and well known biochemical action and effects of both p-aminobenzoic acid and diethylaminoethanol have been used in oral form.

In treating the diseases and ailments that accompany the aging process, quick results cannot be expected. Procaine is a slow acting drug; it is not until the third or fourth month that beneficial effects begin to appear. There are three treatment methods. Gerovital H3 can be taken into the human body orally, in tablet form. Some of the methods have greater absorption than others. Intramuscular injections were received by a large majority of the Parhon Institute patients. However, it is the slower of the methods, taking a much longer time to achieve the desired results. The intravenous or intra-arterial injections will react on the patient quicker. In the case of either method, a competent doctor must perform the treatments. An oral tablet would be well received by all the people of the world as an economical substitute.

Although GH3 is non-toxic, non-habit forming, and produces no side effects, the patients at the Institute still were tested for any reaction to the drug prior to undergoing the full treatment. This should be a standard practice with any patient prior to GH3 therapy. The patient is given a small quantity of GH3 in a subcutaneous (under the skin) injection. Should the patient's reaction to the small injection be negative, another injection of 2 ml is given intramuscularly (deep into the muscle tissue). If again the patient shows a negative reaction to the injection, the full GH3 treatment may be given in complete safety. It must be remembered that the ingredient of GH3, PABA and diethylaminoethanol, is well tolerated in the body. Many doctors use oral preparations containing either ingredient for treatment and obtain gratifying results.

The course of treatment, whether intramuscular, intravenous, or oral, as modified and perfected by Dr. Aslan, consists of one injection of 5 ml of GH3 three times a week for four weeks. As stated above, GH3 has a very slow reaction in the ailment or disease, as the inroads into the affliction are slow in developing. A second course of twelve to sixteen injections is given following a mandatory ten-day rest period. Since GH3 is non-toxic and non habit forming, as many courses as a doctor deems necessary can be administered. However, the ten-day recuperative period must be observed. The Rumanian doctors subscribe to this schedule of injections of GH3 therapy for elderly people. A preventive course of GH3 therapy injections given middle-aged persons for retarding the aging process is slightly different. The Rumanian method of twelve to sixteen injections is followed by one to two months' resting period; then another series of twelve to sixteen injections is given. This treatment could, and usually does, go on indefinitely to forestall the aging process.

The oral method should follow the same sequence of treatment as described above for the injection method. The inconvenience of taking GH3 injections over a long period emphasizes the necessity of perfecting another method to provide this important and valuable treatment for more people. It would be interesting if through this other method the cost could be reduced, so that economics would not prevent people from enjoying the benefits of anti-aging GH3.

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